Comparison of proliferation and differentiation of osteoblasts derived from different locations in patients with adolescent idiopathic scoliosis
نویسندگان
چکیده
Methods From January 2011 to May 2012, a total of 16 AIS patients (14 females, 2 males) were recruited in the study, with age from 11 to 17 years. All patients received posterior spinal fusion and instrumentation, as well as thoracoplasty. Trabecular bone chips from ribs, lamina and iliac crest were harvested in each patient intraoperatively for osteoblast culture. P2 cells were used for the experiment. Proliferation and differentiation of osteoblasts were investigated by using MTT method and alkaline phosphatase (ALP) activity, respectively. One-way analysis of variance (ANOVA) was used for comparison of proliferation and differentiation among osteoblasts derived from different locations.
منابع مشابه
Comparison of Respiratory Muscle Electromyography between Adolescent Idiopathic Scoliosis and Healthy Subjects
Purpose: Scoliosis is one of the most common spinal deformities that affect chest wall mechanics. Scoliosis results in ventilator disorders and respiratory muscle weakness. However, the mechanism of these disorders is still unknown. The main objective of this study was to identify the intensity of respiratory muscles activity in patients with idiopathic scoliosis compare with healthy indi...
متن کاملEvaluation of Patient Outcome and Satisfaction after Surgical Treatment of Adolescent Idiopathic Scoliosis Using Scoliosis Research Society-30
Background: Adolescent idiopathic scoliosis (AIS) may lead to physical and mental problems. It also can adversely affect patient satisfaction and the quality of life. In this study, we assessed the outcomes and satisfaction rate after surgical treatment of AIS using scoliosis research society-30 questionnaire (SRS-30). Methods: We enrolled 135 patients with AIS undergoing corrective surgery...
متن کاملProximal junctional kyphosis in adolescent idiopathic scoliosis following segmental posterior spinal instrumentation and fusion minimum 2 years follow-up
Abstract Background: To evaluate proximal junctional segment changes in Adolescent Idiopathic Scoliosis(AIS) the posterior spinal fusion and also instrumentation also and finding of probable risk factors, were all considered in this study. Methods: We retrospectively reviewed radiographs of 121 consecutive patients who underwent posterior spinal fusion for AIS from T3 or below, with...
متن کاملمقایسه میزان تراکم استخوان دختران مبتلا به اسکولیوز ایدیوپاتیک با افراد بدون اسکولیوز
Background: Several studies have suggested higher incidence of osteoporosis in patients with idiopathic scoliosis in comparison with the normal population. The aim of this study was to assess the prevalence of low bone mass among adolescent girls with idiopathic scoliosis.Methods: In this cross-sectional study performed in shafa Hospital in Tehran, Iran during 2011-2012, we recruited fifty-seve...
متن کاملAssessment of Coronal Radiographic Parameters of the Spine in the Treatment of Adolescent Idiopathic Scoliosis
Background: To determine the most important preoperative factors that affect postoperative coronal parameters of scoliotic curves. Methods: All Adolescent Idiopathic Scoliosis (AIS) patients included in the study were classified according to Lenke and King Classification. The fusion levels were selected according to the rigidity of the existing curves (correction less than 50%), tilt...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 10 شماره
صفحات -
تاریخ انتشار 2015